Note: this page has not been peer reviewed yet, however, all references to have been peer reviewed.


Low Dose Naltrexone (LDN) is currently being used by over 15,000 people in Norway (1).

Many scientists and doctors claim that LDN can have effect on Alzheimer’s disease, Parkinson’s disease, different types of cancer, multiple sclerosis and 170 other illnesses and diseases (2).

This video from explains how it works:

LDN In Literature

Medicor Cancer

Quote from

What is LDN?

LDN stands for “Low Dose Naltrexone”. Naltrexone is a drug that blocks the effects of drugs called opioids. Codeine, morphine, heroin, hydromorphone, oxycodone and methadone are examples of opioids. Naltrexone has been used as a treatment for addiction to opioids and also to alcohol.

Naltrexone comes in a 50mg tablet, but it has been used in low doses of 3-4mg a day by Dr. Bernard Bihari (a neurologist in New York) for treatment of various immune diseases as well as cancer. This is why it is referred to as “low dose” when it is used as a cancer treatment.

LDN works by boosting the levels of a natural opioid in the body called OGF (opioid growth factor). LDN blocks the OGF receptors (also called zeta receptors) temporarily, which triggers the body to make more OGF to counteract the blocking effect. It has been discovered that many cancers respond to the increased levels of OGF, and their growth can be stopped or slowed down.

OGF can be administered directly instead of LDN, but is must be given by injection, and is much more costly.

Does LDN really work?

Dr. Bihari has treated about 450 cancer patients with LDN, and he reports that:

  • over 270 (60%) had significant benefits from LDN
  • 86 of those (25%) “have shown objective signs of significant tumor shrinkage, at least a 75% reduction.”
  • 125 patients (35%) “have stabilized and/or are moving toward remission.”
  • Source:

Here is a list of the cancer types which have shown a response to LDN:

  • Bladder Cancer
  • Malignant Melanoma
  • Breast Cancer
  • Multiple Myeloma
  • Carcinoid
  • Neuroblastoma
  • Colon & Rectal Cancer
  • Ovarian Cancer
  • Glioblastoma
  • Pancreatic Cancer
  • Liver Cancer
  • Prostate Cancer (untreated)
  • Lung Cancer (Non-Small Cell)
  • Renal Cell Carcinoma
  • Lymphocytic Leukemia (chronic)
  • Throat Cancer
  • Lymphoma (Hodgkin’s and NHL)
  • Uterine Cancer

Full paper: LDN-FAQs.pdf

LDN Documentary Video from Norway

From (3):

Title: Unknown medicine LDN gives hope to thousands of patients

Many scientists and doctors claim that LDN can have effect on Alzheimer’s disease, Parkinson’s disease, different types of cancer, multiple sclerosis and 170 other illnesses and diseases.

On of February 2013, Norway’s biggest commercial TV channel TV 2 Norway broadcasted an 18 minute story on the medicine LDN.

The story was part of TV 2’s popular series «Vårt lille land» («Our small country»), a 60 Minutes-inspired documentary show. The episode received record ratings in its time slot and immediately led to widespread discussions on blogs and web forums about LDN. Two months after the story the number of patients using LDN in Norway went from 400 to 4000.

It also changed many doctor’s attitude towards LDN, turning a widespread skepticism towards this unfamiliar drug into a willingness to prescribe LDN at patient’s requests.

See the story about LDN in the video above the article (English subtitles)

In the story four patients with different diseases such as MS, Fibromyalgia, chronic fatigue syndrome, chest infections, breast and lunge cancer told how LDN had helped them back into living relatively normal lives. The Irish Doctor Edmond O’Flaherty stated that he had prescribed LDN to more than 300 patients, and said he was convinced many of them would be dead had they not received this drug.

See the 18-minute video documentary at (3).

How does LDN work?

See videos showing how LDN works (4).


Quote from Beyond DCA (5):

LDN, Low Dose Naltrexone. I am told that although this is not a stand-alone therapy, all cancer patients should take LDN as it aids many other therapies. 4.5 mg per day. Take a 50 mg pill and add 50 ml of water using a baby syringe. Then take 4.5 ml of the mix daily. Your total monthly cost is about $8.00. You can order LDN online.

There is even an LDN Tracker app from the LDN Research Trust (10) which allows you to track your LDN usage and health. This tracker app is used to drive new research on what conditions LDN is effective for.



This is probably one of the safest cancer interventions possible. The drug is FDA approved (6), is safe and non-toxic, and is supported by many clinical trials (7).

Low Dose Naltrexone (LDN) is currently being used by over 15,000 people in Norway (1).

Low Dose Naltrexone has none of the unwanted side effects associated with chemotherapy, in fact, it has no unwanted side effects at all:

  • Your hair will not fall out.
  • No light sensitivity.
  • No nausea.

Special warnings and precautions for use (see video at

  • Adverse reaction with opioids – severe vomiting – ensure no opioid use such as morphine, heroin, hydromorphone, oxycodone and methadone.
  • Confirm normal kidney and liver function.
  • Some elderly patients on 300 milligrams (mg) of naltrexone develop abnormal liver function tests.
  • No evidence of toxicity in volunteers receiving 800 milligrams(mg)/day for seven days.
  • Prolonged use at 50 milligrams (mg) is acceptable, duration of treatment not limited.

Clinical experience using low dose naltrexone 4.5 milligrams (mg) since 2004 (see video at

  • Have not seen abnormal liver function.
  • It is not necessary to monitor liver function with low dose naltrexone.


Yes. The balance of evidence indicates that it is safe and effective.

Low Dose Naltrexone (LDN) can be used in conjunction with any other cancer fighting therapy, including chemotherapy [citation required].

This is probably one of the safest cancer interventions possible, and comes highly recommended.

Appendix A

How are Low Dose Naltrexone and this picture linked?

Note: This section has not been peer reviewed.

We know that Low Dose Naltrexone is effective against cancer.

See if you can work out how Low Dose Naltrexone could possibly be linked to this picture showing how melanoma was treated with Cannabis Oil:


On the surface, Low Dose Naltrexone has little to do with Cannabis Oil:

  • Cannabis is illegal in many countries, whereas Low Dose Naltrexone is avaiable as a prescription;
  • Low Dose Naltrexone is designed to block the effects of opioids such as heroin;
  • Cannabis is not classified an opoid, it is classified as cannaboid.

However, as far as cancer is concerned, they could be both linked:

  • The opiod receptors are targeted by Low Dose Naltrexone;
  • The opiod receptors are targeted by Cannabis (11), which is why medical marijuana is used for pain relief.

So we could have an interesting link:

  • Low Dose Naltrexone works against cancer when taken orally;
  • Cannabis Oil works against cancer, when topically applied to the skin;
  • Both of these appear to work by blocking the Opiod Growth Factor (OGF) receptors temporarily, which stimulates the body to produce more OGF to counteract the effect.

Incidentially, many people have used cannabis oil by itself to cure cancer, see



4 thoughts on “Low Dose Naltrexone (LDN)

  • October 20, 2016 at 5:17 pm


    Thank God Almighty that lead me to Rick Simpson, My husband lungs cancer has been cured within the Rick Simpson Hemp oil. My husband has been through chemo 3 times, but this time his condition was getting worse that I was afraid it will kill him. When a friend of mine directed me to Rick Simpson at: ( where I could buy the medication from, because the Rick Simpson has help cured his own Brain tumor and I strongly recommend that he would helped me with my husband cancer and cure it completely, I never believed the story, but today, with thanks giving in my heart, My husband lungs cancer has been cured within the Rick Simpson hemp oil and I want you all to join hands in appreciation of the great work that is been done by rick Simpson, he is the man that saved the life of my husband with hemp oil, thanks to him. for all those who have problem relating to cancer and other diseases should contact him through his email:( I’ll keep thanking him because his God sent to save my family that was at the stage of collapsing all because of my husband cancer. Emil Bucher, From Thailand..View Link


  • February 5, 2017 at 8:12 am

    I am unable to post this in the Success Stories for whatever reason, so I posted here. I was diagnosed with prostate cancer on October 18, 2013. I was advised by my doctor that my only options were to get a prostatectomy or have radiation seeds implanted in my prostate or receive regular external beam radiation. I declined. I knew there had to be other options.

    I scoured the Internet and discovered a wealth of information about cannabis oil curing cancer. I was able to obtain some medical marijuana oil (Williams Luna) from it and consumed the recommended dosage by mid January. On January 26th I had a cancer reassessment which consisted of an MRI with a state of the art Tesla 3 MRI machine. Results – NO SIGN OF CANCER! CANCER FREE! One of the things that helped me while going through all this was reading the testimonials and the success stories of those who have used the oil and were cured And with good food diet. Now that this wonderful oil has cured me, I feel I need to let others know as well. Please feel free to contact Dr Williams Luna at: .were i purchased the medication oil from. Thank you, Dr Williams Luna

  • March 6, 2017 at 8:13 am

    I have multiple myeloma.  I am about 2.2 on the Gamma test.  I have begun taking LDN for two days now at a dosage of 2.5 mg.  How do I determine the right dosage if it is working or not?

    Lester W Medeiros
    P.O Box 240220
    Honolulu, Hawaii   06824
    (808) 227-3246.

  • March 6, 2017 at 8:30 am

    What am on a ketogenic diet presently.  My gamma score is about 2, the normal range .5-1.5.  Is there any complimentary supplements that would work synergistically with LDM?  What about fucoidan?


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