Cancer and the Ketogenic Diet
Cancer cells depend so much on sugar that is you deprive them of glucose, it shrinks cancer tumors. This is what the Ketogenic diet is based on. Quote from CBN (8):
All cells, including cancer cells, are fueled by glucose. But if you deprive them of glucose, they switch to the alternate fuel, ketone bodies.
Except cancer cells. A defect prevents them from making the switch to using ketone bodies as fuel and therefore, cancer cells can only survive on glucose. All other cells can use either glucose or ketone bodies.
“Your normal cells have the metabolic flexibility to adapt from using glucose to using ketone bodies. But cancer cells lack this metabolic flexibility. So we can exploit that,” Dr. D’Agostino explained.
People like Hatfield, who want to deprive their cells of glucose and fuel them with ketone bodies instead, eat what’s known as a ketogenic diet. It consists of almost zero carbohydrates, but lots of natural proteins and fats.
If you search www.pubmed.org for “ketogenic cancer” or “ketogenic glioblastoma”, you get:
- A study that proves that the ketogenic diet shrinks tumors in mice (3).
- A meta study published in April 2015 that shows that the Ketogenic diet is effective against glioblastoma cancers (1).
- A study published in December 2014 that shows that the Ketogenic diet plus bevacizumab is effective in 6 out of 7 cases of glioblastoma (2).
If you watch The Khan Hippocrates Lecture on DCA Therapy (4), he mentions at the end that they are investigating combining the Ketogenic Diet with DCA:
If you have cancer, the Ketogenic diet may not cure you completely, but it may work well in combination with other therapies.
- (1) Maroon JC, Seyfried TN, Donohue JP, Bost J. The role of metabolic therapy in treating glioblastoma multiforme. Surg Neurol Int 2015;6:61. Available FREE in open access from: http://www.surgicalneurologyint.com/text.asp?2015/6/1/61/155259
- (2) Int J Oncol. 2014 Jun;44(6):1843-52. doi: 10.3892/ijo.2014.2382. Epub 2014 Apr 11. ERGO: a pilot study of ketogenic diet in recurrent glioblastoma by Rieger J et. al. from http://www.ncbi.nlm.nih.gov/24728273.
- (3) PLoS One. 2015 Jun 8;10(6):e0129802. doi: 10.1371/journal.pone.0129802. eCollection 2015. Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model. by Morscher RJ et. al. from http://www.ncbi.nlm.nih.gov/26053068.
- (4) www.youtube.com – Khan Hippocrates Lecture on DCA Therapy.